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작성일 : 12-07-17 16:56

(2005) Proteomics and physiology of erythritol producing strains.

글쓴이 : 박용철

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http://www.sciencedirect.com/science/article/pii/S157002320400892X [1019]

Proteomics and physiology of erythritol producing strains.

Yong-Cheol Park, Do-Yup Lee, Dae-Hee Lee, Hyo-Jin Kim, Yeon-Woo Ryu and Jin-Ho Seo*
Journal of Chromatography B 815(1-2): 251-260. 2005.02.05.
(SCI I/F:2.888)

In-depth knowledge bases on physiological properties of microbes are required to design a better microbial system at a gene level and to develop an industrially viable process in an optimized scheme. Proteomic analyses of industrially useful microorganisms are particularly important for achieving such objectives. In this review, industrial application of erythritol in food and pharmaceutical areas and proteomic techniques for erythritol-producing microbes were presented. Proteomic technologies for erythritol-producingstrains such as Candida magnoliae contained protein or peptide sample preparation for two-dimensional electrophoresis and mass spectrometry, analysis of proteome with matrix assisted laser desorption-ionization/time-of-flight mass spectrometry, liquid chromatography/electrospray ionization/tandem mass spectrometry and similarity searching algorithms. The proteomic information was applied to predict the carbon metabolism of erythritol-synthesizing microorganisms.

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